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Abstract
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In this study, an efficient method for the synthesis of new cyclophanes (5a–f, 6a–g) through the
condensation of 1,4-phenylenedimethanamine (3) or 2,3,5,6-tetramethylbenzene-1,4-diamine (4) with 2-
substituted vinamidiniums (2a–g) is described. The cyclophane derivatives are obtained in good to
excellent yields in the presence of acetic acid in refluxing acetonitrile after 15 h. The structure of new
compounds was validated based on their spectral data (1H NMR, 13C NMR, IR) and elemental analysis.
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