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Keywords
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amines, Europhtal catalyst (8020), organometallic catalysts, Thioamides, thiols
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Abstract
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The potential of industrial cobalt phthalocyanines in the synthesis of thioamides
is reported. A mixture of an industrial sulfonated cobalt phthalocyanines
known as Co[(SO3Na)2,3Pc] (Europhtal catalyst additive 8020) is
introduced as an efficient catalyst capable of converting benzyl thiols to
synthetically valuable thioamides by reaction with amines and DMSO. In this
procedure, different primary and secondary amines also heterocyclic amines
were successfully converted into benzothioamides in high yields. This simple,
one-pot three-component conversion method is scalable and provides efficient
and practical route to the synthesis of diverse benzothioamides.
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