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Title
One-pot sequential synthesis of fused and non-fused poly-substituted dihydropyridine derivatives under catalyst-free conditions
Type Article
Keywords
Dihydropyridine One-pot α,β-Unsaturated aromatic ketones Condensation reaction
Abstract
A one-pot, sequential, three-component procedure is reported for the synthesis of poly-substituted dihydropyridines via the condensation reaction of diamines or aminophenoles, 1,1-bismethylmethio-2-nitroethylene and α,β-unsaturated aromatic ketones in acetonitrile under reflux conditions. A range of fused and non-fused polysubstituted dihydropyridines were prepared in good to high yields with short reaction times.
Researchers fatemeh asilpour (First researcher) , Dariush Saberi (Second researcher) , Alireza Hasaninejad (Third researcher)