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Title
Efficient method for the direct preparation of amides from carboxylic acids using tosyl chloride under solvent-free conditions
Type Article
Keywords
Amide; Solvent-free; Ammonium salts; Tosyl chloride
Abstract
A simple, clean and highly efficient solvent-free procedure for the preparation of primary, secondary, tertiary and aromatic amides is described from the direct reaction of carboxylic acids and silica-supported ammonium salts, triethylamine (TEA) and tosyl chloride (TsCl) as condensing agent.
Researchers Ali Khalafi-Nezhad (First researcher) , Abolfath Parhami (Second researcher) , Mohammad Navid Soltani Rad (Third researcher) , Abdolkarim Zare (Fourth researcher)