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Title
Highly Regioselective N-Alkylation of Benzotriazole under Solvent-Free Conditions
Type Article
Keywords
N-Alkylation, Benzotriazole, Solvent-free, Thermal, Microwave
Abstract
An efficient, simple and solvent-free method for highly regioselective N-alkylation of benzotriazole in the presence of SiO2, K2CO3 and tetrabutylammonium bromide (TBAB) under thermal and microwave conditions has been described. In this method, 1-alkyl benzotriazoles were obtained regioselectively in moderate to high yields and short reaction times.
Researchers A. Khalafi-Nezhad (First researcher) , Abdolkarim Zare (Second researcher) , A. Parhami (Third researcher) , M. N. Soltani Rad (Fourth researcher) , G.R. Nejabat (Fifth researcher)