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Abstract
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Conjugated 1,3-diynes are structural moieties often found in natural products with prominent biological activities, such as antibacterial, antimicrobial, antifungal, antitumor,
anticancer, anti-HIV, and pesticidal agents.[1] This unit plays an important role in molecular recognition as well as in the design of advanced materials
such as conjugated polymers, liquid crystals, molecular wires, or non-linear optic materials, amongst others.[2] Copper nanoparticles on charcoal catalyzed oxidative homo-coupling of terminal alkynes at room temperature under solvent-free conditions. The corresponding 1,3-diynes were obtained in good to high yields.
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