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Title
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آناليز بيوانفورماتيكي بيان متمايز ژن ها در بيماران مبتلا به ديابت نوع 2 و گرفتگي عروق كرونري به منظور معرفي بيوماركرهاي اختصاصي گرفتگي عروق كرونري
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Type
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Presentation
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Keywords
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Type 2 diabetes mellitus, CAD, Biomarker, Bioinformatics analysis, Inflammation
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Abstract
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Type 2 diabetes mellitus is a chronic disorder with growing prevalence in the world. Patients with T2DM suffer from complications which lead to mortality. Coronary artery disease (CAD) is a chronic complication of T2DM which develops in about 60% of patients with T2DM and increase the risk of heart attack. The quest for biomarkers to identify T2DM patients with CAD in early stages has received major interest in recent years. This study aims to find differentially expressed genes in peripheral bloods of T2DM patients versus CAD patients to introduce CAD-specific candidate biomarkers. The gene expression datasets of GSE26168 (T2DM patients) and GSE23561 (patients with CAD) were utilized in bioinformatics analysis. The analysis was carried out by GEO2R. The adjusted P value ?2.0 or log FC?
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Researchers
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Amirhossein Ahmadi (First researcher)
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