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Title
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Synthesis, Characterization, Spectral Studies, Antibacterial Evaluation, Thermodynamics and DFT Calculations of Dimethyltin(IV) Dichloride Schiff Base
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Abstract
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A number of new 1:1 complexes of SnMe2Cl2 with unsymmetrical tetradentate Schiff base ligand with NNOS coordination
sphere have been synthesized and fully characterized by a variety of physico-chemical techniques viz. elemental
analysis, molar conductivity, 1H and 119Sn NMR, IR and mass spectroscopy. IR spectral data show that the fifth coordination
position of tin atom is occupied by an oxygen atom of Schiff base ligands. In the light of titled techniques, trigonal
bipyramidal geometry around the tin atom is proposed for the synthesized complexes. The in vitro antibacterial activities
of the complexes against Staphylococcus aureus and Escherichia Coli have been studied. It was found that they
possess significant antibacterial activity. Also, DFT/B3LYP method was used to analyze the electronic structures and
study of the geometries. The thermodynamic formation constants of the complexes were determined spectrophotometrically
at 25 °C in DMF solvent.
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