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Abstract
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A simple, efficient procedure for the synthesis of 11-(1H-pyrrol-1-yl)-11H-indeno[1,2-b]quinoxaline
and 3-(1H-pyrrol-1-yl)indolin-2-one derivatives in aqueous media is described. The condensation
reaction between 4-hydroxyproline and isatin derivatives or 11H-indeno[1,2-b]quinoxalin-11-ones,
using a catalytic amount of Zr(NO
3
)
4
as a water tolerant Lewis acid catalyst affords, the title
compounds in high to excellent yields and in short reaction times.
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