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Title
Copper catalyzed reaction of alcohols, alkyl halides and Na2S2O3: An odorless and ligand-free rout to unsymmetrical thioether synthesis
Type Article
Keywords
thioether, Na2S2O3, thiol, Bunte salt
Abstract
A CuI-catalyzed condensation reaction between alcohols, alkyl halides, and Na2S2O3 leading to structurally diverse thioethers is reported. A variety of alkyl halides and electron-rich benzyl alcohols were employed successfully in the presence of 5 mol% CuI in PEG-200 at 110 C. The method does not require any ligands or additives. The unsymmetrical thioethers were achieved in good to excellent yields within appropriate reaction times.
Researchers Mohammad Abbasi (Second researcher)