Abstract
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A CuI-catalyzed condensation reaction between alcohols, alkyl halides, and Na2S2O3 leading to structurally diverse
thioethers is reported. A variety of alkyl halides and electron-rich benzyl alcohols were employed successfully in the
presence of 5 mol% CuI in PEG-200 at 110 C. The method does not require any ligands or additives. The unsymmetrical
thioethers were achieved in good to excellent yields within appropriate reaction times.
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