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Title
One-pot synthesis of pyridopyrimidines via reaction of enaminones or uracils with in situ generated Chalcones
Type Presentation
Keywords
pyridopyrimidine; quinoline; chalcone; enaminone; uracil
Abstract
A one-pot reaction is presented for the synthesis of pyridopyrimidine and quinoline derivatives, which are nitrogen-containing heterocyclic compounds with various medicinal properties. Chalcone derivatives are generated in situ from the reaction of aldehyde and ketone derivatives, then trapped by enaminone or uracil to produce the corresponding pyrido[2,3-d] pyrimidine and quinoline derivatives.
Researchers Najmeh Nowrouzi (Second researcher)