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Title
A Highly Efficient Protocol for the Synthesis of N-Aryl Nucleobases Using Zinc Oxide in Ionic Liquids
Type Article
Keywords
N-Aryl nucleobase, Zinc oxide, Ionic liquid, N-Arylation, Microwave
Abstract
A highly efficient and simple method for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases via Narylation of nucleobases using zinc oxide in 1-butyl-3-methylimidazolium bromide ([bmim]Br) under microwave as well as thermal conditions is described. In both conditions, the title compounds were produced in high to excellent yields and in short reaction times.
Researchers Abdolkarim Zare (First researcher) , A. Hasaninejad (Second researcher) , A. Khalafi-Nezhad (Third researcher) , A.R. Moosavi Zare (Fourth researcher) , M.H. Beyzavi (Fifth researcher) , F. Khedri (Not in first six researchers) , F. Asadi (Not in first six researchers) , N. Hayati (Not in first six researchers) , A. Asifi (Not in first six researchers)