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Title
Highly efficient synthesis of triazolo[1,2-a]indazole-triones and novel spiro triazolo[1,2-a]indazole-tetraones under solvent-free conditions
Type Article
Keywords
Combinatorial chemistry; Multi-component reaction; PEG-SO3H Urazole; Triazolo[1,2-a]indazole-triones; Spiro triazolo[1,2-a]indazole-tetraone
Abstract
A new, convenient, and high yielding procedure for the synthesis of triazolo[1,2-a]indazole-triones by the condensation reaction between dimedone, aryl aldehydes, and ueazoles in the presence of a catalytic amount of sulfonated polyethylene glycol (PEG-SO3H) as a highly stable and reusable eco-friendly degradable polymeric catalyst is described under solvent-free conditions. This procedure has also been applied successfully for the synthesis of novel spiro triazolo[1,2-a]indazole-tetraones.
Researchers Alireza Hasaninejad (First researcher) , Abdolkarim Zare (Second researcher) , Mohsen Shekouhy (Third researcher)