Research Info

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Title
[Et3N‑SO3H][MeSO3] as a highly efficient catalyst for the production of pyrido[2,3‑d:6,5‑d′]dipyrimidines and bis(pyrazolyl)methanes
Type Article
Keywords
[Et3N-SO3H][MeSO3]; Acidic ionic liquid; Pyrido[2,3-d:6,5-d′]dipyrimidines; Bis(pyrazolyl)methanes; One-pot multi-component reaction; Solvent-free conditions
Abstract
In this research, highly efficient protocols for the production of pyrido[2,3-d:6,5-d′]dipyrimidine and bis(pyrazolyl)methane derivatives using an acid ionic liquid namely [Et3N-SO3H][MeSO3] have been reported (bis(pyrazolyl)methanes have been produced via two methods, the pseudo three-component and the pseudo five-component reactions). [Et3N-SO3H][MeSO3] was superior than many of the reported catalysts in terms of two or more of these factors: turnover frequency (TOF), turnover number (TON), the reaction temperature, yield, the reaction time, simplicity in workup, and the reaction conditions.
Researchers Abdolkarim Zare (First researcher) , Alireza Kohzadian (Second researcher) , Hossein Filian (Third researcher) , Mariam Sadat Ghoreishi Nezhad (Fourth researcher) , Amirali Karami (Fifth researcher)