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Keywords
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N,N-Dialkyl sulfonamide, Solvent-free, Michael addition, α,β-Unsaturated ester, NaOH, Microwave
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Abstract
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Aza-Michael addition of sulfonamides to α,β-unsaturated esters efficiently proceeds in the presence of catalytic amount of sodium hydroxide (NaOH) and tetrabutylammonium bromide (TBAB) as a phase-transfer catalyst (PTC) under microwave irradiation to afford N,N-dialkyl sulfonamides as biologically interesting compounds in good to excellent yields and short reaction times.
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