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Title
Synthesis of 6-amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles using disulfonic acid imidazolium chloroaluminate as a dual and heterogeneous catalyst
Type Article
Keywords
6-Amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles; disulfonic acid imidazolium chloroaluminate; dual and heterogeneous catalyst; multi-component condensation
Abstract
In this work, disulfonic acid imidazolium chloroaluminate {[Dsim]AlCl4} is applied as a new acidic and heterogeneous catalyst for green, simple and efficient synthesis of 6-amino-4-(4-methoxyphenyl)-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles by the one-pot multi-component condensation of aryl aldehydes with ethyl acetoacetate, malononitrile and hydrazine hydrate at 80 °C under solvent-free conditions.
Researchers Ahmad Reza Moosavi-Zare (First researcher) , Mohammad Ali Zolfigol (Second researcher) , Ehsan Noroozizadeh (Third researcher) , Mahsa Tavasoli (Fourth researcher) , Vahid Khakyzadeh (Fifth researcher) , Abdolkarim Zare (Not in first six researchers)