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Title
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One-pot multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles using sulfonic acid-functionalized pyridinium chloride as an efficient and recyclable catalyst
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Abstract
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Sulfonic acid-functionalized pyridinium chloride ionic liquid {[Pyridine–SO3H]Cl} can effectively promote the one-pot multi-component condensation reaction between benzil, aldehydes, primary amines and ammonium acetate under solvent-free conditions at 100 ºC to give the desired 1,2,4,5-tetrasubstituted imidazoles, in high yields and short reaction times.
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