24 تیر 1403
عبدالصالح زر

عبدالصالح زر

مرتبه علمی: دانشیار
نشانی: دانشکده ادبیات و علوم انسانی - گروه علوم ورزشی
تحصیلات: دکترای تخصصی / فیزیولوژی ورزش
تلفن: 09387228086
دانشکده: دانشکده ادبیات و علوم انسانی

مشخصات پژوهش

عنوان Effect of Resistance Training and Spirulina platensis on Expression of IL-6, Gp130 Cytokines, JAK-STAT Signaling in Male Rats Skeletal Muscle
نوع پژوهش مقالات در نشریات
کلیدواژه‌ها
Resistance training; Spirulina platensis; IL-6; Jak; STAT
مجله MCB Molecular and Cellular Biomechanics
شناسه DOI
پژوهشگران عبدالصالح زر (نفر اول) ، فاطمه احمدی (نفر دوم) ، فروزان کریمی (نفر سوم) ، مژگان احمدی (نفر چهارم) ، روگر رامسبوتوم (نفر پنجم)

چکیده

The effect of resistance training and a herbal supplement on muscular signaling pathways are limited. We investigated the expression of IL-6, Gp130, JAK and STAT after resistance training, and Spirulina platensis supplementation in animal muscle. Thirty-two male Sprague Dawley rats (weight: 290 ± 20 g, and 9 weeks of age) were divided into four groups: control (CO; n = 8), Spirulina platensis supplementation (SP; n = 8), resistance exercise (RE; n = 8), and Spirulina platensis + resistance exercise (SP + RE; n = 8). The resistance exercise group trained five sessions each week for eight weeks. Spirulina 200 mg kg−1 d−1 was used in the SP and SP + RE groups. Gene expression was measured by real-time PCR following the last training session. One-way ANOVA test with Tukey’s post-hoc test were used for analysis of data (SPSS, version, 21). Data analysis revealed that the expression of IL-6 (P = 0.001), Gp130 (P = 0.001), JAK (P = 0.0001) and STAT (P = 0.004) increased significantly in the RE group. The expression of IL-6 (P = 0.018), JAK (P = 0.001) and STAT (P = 0.001) in SP + RE group also increased significantly (P ≤ 0.05). SP showed a significant increase in Gp130 (P = 0.001) and STAT (P = 0.001). Supplementation by Spirulina platensis may enhance muscle accretion during resistance training.