February 29, 2024
Abdosaleh Zar

Abdosaleh Zar

Academic Rank: Associate professor
Degree: Ph.D in exercise physiology
Phone: 09387228086
Faculty: Faculty of Humanities


Title Lipid Lowering Eects of Nigella sativa and Swimming Training in Streptozotocin Induced Diabetic Rats
Type Article
Journal annals of military and health sciences research
Researchers Abdosaleh Zar (Second researcher) ,


Background: Diabetes is a chronic disease that causes disorders in blood lipids. Objectives: The purpose of this study was to investigate the lipid lowering e?ects of hydroalcoholic extract of Nigella sativa and swim training in streptozotocin-induced diabetic rats. Methods: A total of 32 diabetic rats were selected and randomly divided into four equal-size groups: (1) Swim training, (2) Nigella sativa, (3) swim training with Nigella sativa, and (4) control. Groups 2 and 3 received 100 mg/kg/day of Nigella sativa extract in the peritoneum. Groups 1 and 3 also swam in a swimming tank (?ve days per week for four weeks). After this period, blood samples were taken. For analysis of the ?ndings, Paired Sample t -test and two-way ANOVA were used (P  0.05). Results: Swim training and Nigella sativa consumption had a signi?cant e?ect in reducing cholesterol (Cho), triglycerides (TG), very low-density lipoprotein (VLDL), and low-density lipoprotein (LDL) (P  0.05); high-density lipoprotein (HDL) increased signi?cantly following swim training (P  0.05); Nigella sativa and swim training had signi?cant interactive e?ects in reducing Cho, TG, VLDL, and LDL, and in increasing HDL (P  0.05). Conclusions: It seems that four weeks of Nigella sativa consumption combined with swimming training has a more favourable fat-reducing e?ect than Nigella sativa consumption or swim training alone.