اسماعیل تماری

Electrochemical oxidation of desipramine (DES) has been studied in the presence of 4,6-dimethylpyrimidine- 2-thiol (DMPT) as nucleophile in acidic medium by means of cyclic voltammetry, controlled-potential electrolysis and spectroscopic data, as diagnostic techniques. Voltammetric studies of electro-oxidation of desipramine were realized in a range of pH 1.0 to 8.0 in the absence and presence of DMPT. The results indicate the participation of the product of electrochemical oxidation of desipramine in the reaction with DMPT with ECEC electrochemical mechanism. However, the voltammetry and coulometry results imply existence of a catalytic (EC’) electrochemical mechanism in parallel with ECEC electrochemical mechanism. The product has been characterized by IR, 1H NMR, 13C NMR and MS methods.