خدابخش نیکنام

Conjugated 1,3-diynes are structural moieties often found in natural products with prominent biological activities, such as antibacterial, antimicrobial, antifungal, antitumor, anticancer, anti-HIV, and pesticidal agents.[1] This unit plays an important role in molecular recognition as well as in the design of advanced materials such as conjugated polymers, liquid crystals, molecular wires, or non-linear optic materials, amongst others.[2] Copper nanoparticles on charcoal catalyzed oxidative homo-coupling of terminal alkynes at room temperature under solvent-free conditions. The corresponding 1,3-diynes were obtained in good to high yields.