In this study, a novel and integrated strategy is proposed to investigate the problem of low production rate of gas well in a supergiant gas condensate reservoir. In this strategy, the nodal analysis approach is applied for production optimization and performance assessment of a real inclined well. A multi-layered gas condensate reservoir model was constructed and simulated using actual reservoir rock and fluid properties. Effects of reservoir rock and fluid model simplification on inflow performance relationship (IPR) curves were investigated. Also, five different tubing pressure drop models were evaluated using extracted pseudo spontaneous potential (PSP) data from reservoir model to select the most accurate one for computing tubing performance relationship (TPR) data. Then, accuracy of nodal analysis in prediction of well operating point was investigated through comparing with reservoir simulator results. Results of nodal analysis for this well indicated that a significant discrepancy exists between calculated and actual production rate. Sensitivity analysis on uncertainty parameters, skin factor and drainage radius, shows that skin factor of the investigated well varies between 11 and 12.9 for drainage radius in the range of 3000–20000 ft. Therefore, the problem of low well production rate was attributed to high skin factor as a result of formation damage. Also, results demonstrated that reduction of skin can lead to maximum 73% enhancement in daily volumetric gas production rate of well.