Carbon quantum dots (CQDs) with good stability and excellent biocompatibility, as a carbon-based nanomaterial, have begun to play an increasingly important role in electrochemical biosensors. In the present study, CQDs were prepared by hydrothermal treatment of dopamine at 180 ?C for a period of 6 h. The obtained dopamine-quantum dots were collected by removing the large dots through centrifugation at 10000 rpm for 10 min. The electrochemical behavior of the dopamine-quantum dots was investigated by cyclic voltammetry using a carbon paste electrode (CPE) as working electrode. The cyclic voltammogram of the quantum dots showed a redox couple with formal potential of 0.181 V. A comparison between the electrochemical behavior of dopamine and the electrochemical behavior of dopamine-quantum dots at the electrode surface showed the dopamine-quantum dots have more peak currents than dopamine. The effect of scan rate, pH and ascorbic acid on the electrode response was also studied.