MS is a disease of the central nervous system that created many challenges in the psychological adjustment of
patients around the world. The aim of this study was to identify predictors of adherence to treatment in patients with
multiple sclerosis MS society in Tehran was in 1392. The above study is based on a descriptive correlation method.
The participants consisted of 120 patients with MS in MS Society in Tehran and the community's support of the MS
patients who were selected based on accessibility.
For all patients, demographic questionnaire, following the treatment of MS patients, general self-efficacy, Neo
character - Short Form, Beck Depression Inventory, Quality of life, anxiety, Panas positive and negative affect,
Social support and feedback Phillips was completed. Data analysis was performed using multivariate analysis of
variance and discriminant analysis and logistic regression analysis. The findings suggest a significant difference for
adherence to depression, Neuroticism, extraversion, conscientiousness appetite, quality of life, Family social
support, and anxiety at a=0.50. The results show that the compliance of the treatment of MS is directly related
psychological factors and to better treat these patients in addition to counseling the drug should reduce anxiety and
depression and increases self-efficacy to improve their quality of life.