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چکیده
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In the chronic exposure of Boleophthalmus dussumier with Benzoalphaapyrene at concentrations of 10, 40, 80 and 100 ?g / L, the expression of CYP1A gene in the liver showed a sudden increase on the first day, and then two different patterns of expression of the gene in treatments with a concentration The bottom and the top of the pollutant were observed. At high concentrations, the expression of the gene increased until the third day, followed by a decreasing trend, while in the lower rats, the increase in gene expression continued until day 21, followed by a decrease in gene expression. At high concentrations, benzo-alpha-phpyrene and its metabolites will have a negative effect on the cells, resulting in a severe reduction in expression. In chronic concentrations of benzo-alpha-phrasin, no degradation effects are expected and the gene expression is increased at a low and continuous level. Therefore, due to the correlation between the expression of CYP1A gene and the concentration of the pollutant and biota in coastal areas and hara ecosystems, it can be shown that the CYP1A gene is expressed as a biomarker of oil pollutants in these ecosystems.
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