مشخصات پژوهش

A very simple and efficient solvent-free procedure for the synthesis of N-alkyl derivatives of phthalimide and saccharin is described. Michael addition of phthalimide and saccharin to acrylic acid esters in the presence of catalytic amount of zinc oxide (ZnO) and tetrabutylammonium bromide (TBAB) under microwave and thermal conditions affords the title compounds. The advantages of this method are high yields, short reaction times, low cost and matching with green chemistry protocols.