|
عنوان
|
Self-catalyzed, reaction of benzyl halides, Na2S2O3,
and amines: a one-pot, simple, and efficient route to
thiobenzamides
|
|
چکیده
|
A new efficient, one-pot method to get thiobenzamide compounds
from benzyl halides, amines, and Na2S2O3 is reported. A benzylic
halide is treated with Na2S2O3 in DMSO until the halide is completely
consumed. Next, the reaction is continued by adding a primary or
secondary amine to the reaction mixture to synthesize thiobenzamides
simply. This procedure does not require a special catalyst or
any additive to afford thiobenzamides in good to excellent yields.
|