مشخصات پژوهش

Propellanes are tricyclics compounds which one of their carbon-carbon single bonds are in common with their three-ring structure and can be find in naturally and non-naturally occurring products. [1- 2] Propellanes and their derivatives have attractive properties due to their unique structure so that they have wide range of applications in biological, medicinal and organic chemistry. [3] In continuous of our previous researches on the chemistry of acenaphthoquinone and 2- nitroethenamines [4], we wish to report here the results of our studies on the reaction of malonated acenaphthoquinone with 2-nitroethenamines. We found when 2-nitroetheneamines (3) were added to a mixture of acenaphthoquinone (1) and malononitrile (2) in ethanol under reflux conditions, propellane derivatives (4) synthesized in good to excellent yields (Scheme). The products (4) were characterized using their spectroscopic data. As a result of our efforts, we developed a new one-pot method for synthesis of some new propellanes having furane and pyrrole moieties.