مشخصات پژوهش

In this work, highly e?cient, green and inexpensive procedures for the preparation of quinoxaline and quinoline derivatives as attractive aza-polycyclic compounds are described. Silica nanoparticles-catalyzed condensation of 1,2-diamines with 1,2-diketones under solvent-free conditions at room temperature a?ords high yields of quinoxalines with short reaction times. Moreover, the microwave-assisted Friedlander hetero-annulation reaction between 2-aminoaryl ketones and carbonyl compounds in the presence of silica nanoparticles (NPs) as catalysts gives high yields of quinoline derivatives with short reaction times. These reactions have been done in neutral conditions. The NPs catalysts can be reused without lost of activity even after recycling fourteen times .