مشخصات پژوهش

Cancer and its treatment have been one of the challenges of humans since the beginning, and much research has been conducted over many years on its treatment methods. In recent years, the use of new and low-complication methods, as well as combined methods, has become increasingly widespread. This study investigated the com- bined process of photothermal and chemotherapy for nanocomposite CoxNi1 xFe2O4∕MoS2. For this purpose, nanocomposite has been synthesized using a facile sol-gel and hydrothermal method. The structure and shape of nanostructures have been investigated using X-ray diffraction patterns, scanning electron microscopes, and transmission electron microscope images. The results confirmed the formation of CoxNi1 xFe2O4 nanoparticles with an approximate size of 55.44 nm, substituted in nanosheets MoS2. The results of UV–visible adsorption show that the synthesized nanocomposites have band gaps of 1.65 eV and 1.48 eV for nanostructures CoFe2O4∕MoS2 and Co0.5Ni0.5Fe2O4∕MoS2, respectively. Also, the photothermal efficiency of nanocomposites CoFe2O4∕MoS2 and Co0.5Ni0.5Fe2O4∕MoS2 irradiated with 808 nm diode laser and 1-watt power density are 31 % and 26 %, respectively. The loading rate of doxorubicin drug in nanocomposite is ~ 60 %.